No, but I know of a RemoteWonder driver that will install and function in Vista with nary an issue.
Download RW driver 1.4. Right click on the executable, click on the compatibility tab, and select XPSP2 compatibility mode. Close the dialogue box. Again, right click on the executable and left click "run as administrator."
That's it. Install and reboot. I suggest having your RW unplugged during your OS install, and then install RW drivers immediately after installing Vista (or XP). Reboot after the driver install and when you get to the desktop, plugin the remote.
If you've already installed Vista, and you install RW drivers but have no systray icon, you can try my fix in a seperate thread.