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    Originally posted by KAC View Post
    Sorry to hear that Lazy. My fam is still coughing but fever has subsided. Little kid seems fully recovered. Wife second test also came positive so still a few days to go for us.
    I’m glad your boy recovered KAC - I hate watching kids go through an illness, and I hope everyone in your family is healthy and safe soon.

    Comment


      Originally posted by Lazy8s View Post
      The plus side > fully vaccinated. She’s running a fever, but no other symptoms so far, so hopefully it stays that way. Me….Still have a hard time catching my breath, but the fever is gone and the fatigue seems to be letting up.

      Thank God for small blessings
      Originally posted by KAC View Post
      Sorry to hear that Lazy. My fam is still coughing but fever has subsided. Little kid seems fully recovered. Wife second test also came positive so still a few days to go for us.
      Good news guys, glad to hear it.

      Comment


        The SARS-CoV-2 infection determines the COVID-19 syndrome characterized, in the worst cases, by severe respiratory distress, pulmonary and cardiac fibrosis, inflammatory cytokine release, and immunosuppression. This condition has led to the death of about 2.15% of the total infected world population so far. Among survivors, the presence of the so-called persistent post-COVID-19 syndrome (PPCS) is a common finding. In COVID-19 survivors, PPCS presents one or more symptoms: fatigue, dyspnea, memory loss, sleep disorders, and difficulty concentrating. In this study, a cohort of 117 COVID-19 survivors (post-COVID-19) and 144 non-infected volunteers (COVID-19-free) was analyzed using pyrosequencing of defined CpG islands previously identified as suitable for biological age determination. The results show a consistent biological age increase in the post-COVID-19 population, determining a DeltaAge acceleration of 10.45 ± 7.29 years (+5.25 years above the range of normality) compared with 3.68 ± 8.17 years for the COVID-19-free population (p < 0.0001). A significant telomere shortening parallels this finding in the post-COVID-19 cohort compared with COVID-19-free subjects (p < 0.0001). Additionally, ACE2 expression was decreased in post-COVID-19 patients, compared with the COVID-19-free population, while DPP-4 did not change. In light of these observations, we hypothesize that some epigenetic alterations are associated with the post-COVID-19 condition, particularly in younger patients (< 60 years).


        Evidence for Biological Age Acceleration and Telomere Shortening in COVID-19 Survivors

        The results show a consistent biological age increase in the post-COVID-19 population, determining a DeltaAge acceleration of 10.45 &#177; 7.29 years (+5.25 years above the range of normality) compared with 3.68 &#177; 8.17 years for the COVID-19-free population (p < 0.0001). A significant telomere shortening parallels this finding in the post-COVID-19 cohort compared with COVID-19-free subjects (p < 0.0001). Additionally, ACE2 expression was decreased in post-COVID-19 patients, compared with the COVID-19-free population, while DPP-4 did not change. In light of these observations, we hypothesize that some epigenetic alterations are associated with the post-COVID-19 condition, particularly in younger patients (< 60 years).
        the vast majority (76.6&#37 of the post-COVID-19 group had an average DeltaAge acceleration of 10.45 years
        Quotes:

        Rage3d is the BEST forum!! There are alot of smart people on here!! -phexus

        Comment


          Scary stuff.
          Originally posted by KAC
          To be honest I never even found doom 3 to be scary since I have a big dick since birth.

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            10 years removed from my life. No big loss.

            Comment


              Originally posted by KAC View Post
              10 years removed from my life. No big loss.
              errrm, well, that's like, your opinion man.
              i5 4670 Haswell <> Gigabyte radeon 280x <> 8 gigs of some ram that happened to be on sale that week <> Asus Z87-K <> Some DVD burner that has been used for 3-4 computers - might be a pioneer <> Winblows 10 Now!

              Comment


                Today there was no line of cars to get tests at the hospital near my house. The last few weeks the line was hours long. Maybe that’s a good sign the spike has peaked in my area?

                Comment


                  Just got my booster, third Moderna shot. No aftereffect for now.

                  Was able to connect my phone to my small antenna so the 5g signal really is much stronger now.



                  It's like unicorns vomiting chocolate rainbows all over me as I float through a lollipop garden on a magic carpet.

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                  Comment


                    My wife and I are getting the boosters scheduled a few days after we’re in the clear. We want all the protection we can get from this thing.

                    Her symptoms are staying fairly mild thankfully. Me…feeling better every day.

                    Comment


                      Good news Phil, glad to hear it.

                      Comment


                        Originally posted by SD-[Inc] View Post
                        Today there was no line of cars to get tests at the hospital near my house. The last few weeks the line was hours long. Maybe that’s a good sign the spike has peaked in my area?
                        People probably just gave up. The lack of testing sites here is sad. If I get sick, I'll just assume I have it. I'm not sitting in my truck feeling like crud for hours to get a test that won't come back until I'm feeling better or in the hospital.

                        Comment


                          Originally posted by acroig View Post
                          Good news Phil, glad to hear it.
                          Thanks Alex - it’s truly a relief.

                          Comment


                            Originally posted by Greasy View Post
                            People probably just gave up. The lack of testing sites here is sad. If I get sick, I'll just assume I have it. I'm not sitting in my truck feeling like crud for hours to get a test that won't come back until I'm feeling better or in the hospital.
                            I knew someone would rain on my parade like this. I don’t think people “give up”. The line must have been 3 hours long 2 weeks ago. That would have been a much better time to give up.

                            Comment


                              has anyone mixed and matched their shots? two shot moderna + pfizer booster (and vice versa), e.g.
                              i don't think i'll be getting the booster (got two shots of moderna). but, if i change my mind, or if the third shot is what they consider "fully vaccinated", then maybe i'll bite the bullet.
                              "World's First Analyst and Therapist: the Analrapist"
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                              Comment


                                Lots of people in the UK and Canada mixed AstraZeneca with Pfizer/Moderna (which are basically interchangeable).

                                A major British study into mixing COVID-19 vaccines has found that people had a better immune response when they received a first dose of AstraZeneca or Pfizer-BioNTech shots followed by Moderna nine weeks later, according to the results on Monday.
                                My world is a world of concepts and principles, not a battlefield - "war" is simply the wrong metaphor for where I'm coming from.

                                Comment


                                  Originally posted by Payne3d View Post
                                  has anyone mixed and matched their shots? two shot moderna + pfizer booster (and vice versa), e.g.
                                  i don't think i'll be getting the booster (got two shots of moderna). but, if i change my mind, or if the third shot is what they consider "fully vaccinated", then maybe i'll bite the bullet.
                                  I got 2 vaccinations of pfizer and then opted to get the moderna booster. Moderna did knock me out for 24 hours... slept alot and muscles were sore, but was fine the following day.
                                  Originally posted by KAC
                                  To be honest I never even found doom 3 to be scary since I have a big dick since birth.

                                  Ryzen 5 5600x - radeon 6700xt - 32 gigs memory


                                  Nintendo: NES, SNES, N64, Gamecube, Wii, Wii U, Switch, Gameboy, Gameboy Pocket, Gameboy Color, Virtual Boy, 6 GBAs, DS, 3ds
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                                  Sony: PS1, PS2, PS3, PS4, PSP
                                  Microsoft: og xbox, xbox360, xbone, series 3
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                                  Comment


                                    Originally posted by SubCog View Post
                                    I got 2 vaccinations of pfizer and then opted to get the moderna booster. Moderna did knock me out for 24 hours... slept alot and muscles were sore, but was fine the following day.
                                    I should prepare myself for this eventuality.
                                    Im double shot with pfizer but around here it seems like theres moderna boosters aplenty but pfizer boosters are several weeks out and even then theres a line of people waiting for it. So its gonna take a miracle to even get a pfizer booster anytime soon...might just bite the bullet and just get a moderna booster.

                                    I think i would have been be a bit more hesitant since moderna used a higer dosage normally (pfizer used 30mg ingredient for each shot, moderna i think was 100mg) but it seems like the moderna booster is 50mg, so i just want to know if its fine to mix and match.
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                                    Comment


                                      Yes, it's fine to mix them. They're basically the same as far as your immune system is concerned.

                                      Moderna is not recommended for younger men (~15-30) due to an elevated risk of heart inflammation, so that might explain why people want to avoid it. However, this caution does not to apply to females, or prepubescent and older males. I'm actually hoping for a Moderna booster (after two Pfizers), because Moderna's efficacy seems to be holding up better in the long term studies. I'd definitely go for a Moderna booster if you're over 30.
                                      My world is a world of concepts and principles, not a battlefield - "war" is simply the wrong metaphor for where I'm coming from.

                                      Comment


                                        From here:



                                        What do we know about mRNA mixed (heterologous) vaccine schedules?

                                        • The mechanism of action in both Pfizer-BioNTech and Moderna mRNA vaccines is the same. Both use the pre-fusion conformation of the spike protein of the SARS-CoV-2 virus as the antigen. The spike protein encoded by either of the authorized mRNA vaccines is stabilized in the same manner, although other vaccine components like the lipid nanoparticle and the mRNA sequence may be different.

                                        • During clinical trials, both mRNA vaccines (Pfizer-BioNTech, Moderna) demonstrated similar safety profiles and side effects (NACI).

                                        • Both mRNA vaccines showed similar vaccine efficacy in clinical trials against symptomatic COVID-19 disease following the second dose, 95&#37; and 94% respectively for Pfizer-BioNTech and Moderna vaccines (NACI). Recent vaccine effectiveness estimates against symptomatic disease from Ontario have also demonstrated similar estimates of 91% and 94% respectively for Pfizer-BioNTech and Moderna vaccines (Chung et al., 2021).

                                        • There is no reason to believe that mRNA vaccine series completed with a different authorized mRNA vaccine product would result in any additional safety issues or reduction in immune protection against COVID-19 at this time (NACI).
                                        My world is a world of concepts and principles, not a battlefield - "war" is simply the wrong metaphor for where I'm coming from.

                                        Comment


                                          Originally posted by Lazy8s View Post
                                          My wife and I are getting the boosters scheduled a few days after we’re in the clear. We want all the protection we can get from this thing.

                                          Her symptoms are staying fairly mild thankfully. Me…feeling better every day.
                                          that's great news. Good to hear. Hope your wife will be on her feet in no time.


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                                          Comment


                                            Originally posted by Silent-Runner View Post
                                            that's great news. Good to hear. Hope your wife will be on her feet in no time.

                                            Comment


                                              Good friend and his wife tested positive last night. This thing is everywhere.
                                              Originally posted by Ozziebloke
                                              I mean, yeah, sure, there's benefits to a shaved asshole. But get a little sweaty and try and blow a fart. It just sits there like a bubble. No hair to break the seal. Feels weird.



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                                              Comment


                                                I HAVE TESTED POSITIVE!!!!!!!!!!!!!

                                                Owner of the shop I work at tested positive so everyone else tested and we are the only two. I have a bit of a tingle in the back of my throat, but it goes away fast after I wake up in the morning.
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                                                Comment


                                                  Originally posted by Hapatingjaky View Post
                                                  I HAVE TESTED POSITIVE!!!!!!!!!!!!!

                                                  Owner of the shop I work at tested positive so everyone else tested and we are the only two. I have a bit of a tingle in the back of my throat, but it goes away fast after I wake up in the morning.
                                                  With any luck that's the only symptom you get.

                                                  Make sure you thank your boss.

                                                  Comment


                                                    Originally posted by acroig View Post
                                                    With any luck that's the only symptom you get.

                                                    Make sure you thank your boss.
                                                    Oh I already thanked him. Best part we were evicted from the building and bought a new shop. No fault of our own, the company that owns the building wanted more space. Now we can't even move the shop which we started Christmas week lol.
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                                                    Comment


                                                      Originally posted by Hapatingjaky View Post
                                                      Oh I already thanked him. Best part we were evicted from the building and bought a new shop. No fault of our own, the company that owns the building wanted more space. Now we can't even move the shop which we started Christmas week lol.
                                                      Crap, great to start the new year.

                                                      Comment


                                                        So now my niece has got the Rona. That puts my other brother Adam and his family in the crosshairs.

                                                        Sucks too, we're supposed to go ice fishing in Minnesota on Friday. Pretty sure the trip is torpedoed now.

                                                        Comment


                                                          For me its nice to know that I am double vaxed and have my booster. Would my Rona be more severe then if I didn't have it? I dunno, but I am healthy as I am eating some popcorn and chocolate while I type this.

                                                          We have two anti-vaxxers at work and the owners wife just told them that myself and the owner have no symptoms but what if they were to get it. Plus they are smokers so double whammy.
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                                                          Comment


                                                            Oklahoma recorded 27,058 new cases over the weekend with 58 deaths.

                                                            The shocking part is that this is with testing shortages.

                                                            Comment


                                                              Originally posted by Hapatingjaky View Post
                                                              For me its nice to know that I am double vaxed and have my booster. Would my Rona be more severe then if I didn't have it? I dunno, but I am healthy as I am eating some popcorn and chocolate while I type this.

                                                              We have two anti-vaxxers at work and the owners wife just told them that myself and the owner have no symptoms but what if they were to get it. Plus they are smokers so double whammy.
                                                              My 66 year old mother-in-law just tested positive last week. She is triple vaccinated and so far it has just amounted to what she says "felt like a sinus infection for a few days." She is pretty much already over it.

                                                              Same has been the case for almost every vaccinated person I know that tested positive lately. Just very minor symptoms that clear up in about 5 days.

                                                              The unvaccinated people I know that got it however, not so good. The most severe case I know, one of my wife's friends was infected in mid December and is still sick. He had to go to the hospital for a week to be on oxygen. He's home now (they sent him home with oxygen tank) but is still not recovered. Its looking more like he caught the older strain (delta likely).

                                                              Comment


                                                                I'm running a bit of a fever and not feeling all that great. Will probably get tested tomorrow to confirm. I was about to get my booster tomorrow too, mfers lol
                                                                Originally posted by curio
                                                                Eat this protein bar, for it is of my body. And drink this creatine shake, for it is my blood.
                                                                "If you can't handle me when I'm bulking, you don't deserve me when I'm cut." -- Marilyn Monbroe

                                                                Comment


                                                                  Originally posted by Meteor_of_War View Post
                                                                  My 66 year old mother-in-law just tested positive last week. She is triple vaccinated and so far it has just amounted to what she says "felt like a sinus infection for a few days." She is pretty much already over it.
                                                                  That is exactly how I felt last week. Thought I had a sinus infection. Hope I didn't have it, because I just went about life as usual. Nobody in the house had any issues either, so prob just was my sinus acting up. Hell who knows these days.

                                                                  Comment


                                                                    Originally posted by Greasy View Post
                                                                    That is exactly how I felt last week. Thought I had a sinus infection. Hope I didn't have it, because I just went about life as usual. Nobody in the house had any issues either, so prob just was my sinus acting up. Hell who knows these days.
                                                                    Yeah, and should have mentioned the only reason she even took the test is because she was exposed to someone at her work that was sick. She apparently caught it, but thankfully very minor symptoms.

                                                                    Never can say for sure, but we confidently assume the vaccination made the difference.

                                                                    Comment


                                                                      Got my booster today, fully expect to feel sick tomorrow morning.
                                                                      Originally posted by David O. McKay
                                                                      The home is the first and most effective place to learn the lessons of life: truth, honor, virtue, self control, the value of education, honest work, and the purpose and privilege of life. Nothing can take the place of home in rearing and teaching children, and no other success can compensate for failure in the home.
                                                                      Originally posted by Albert Einstein
                                                                      Imagination is more important than knowledge. For knowledge is limited to all we now know and understand, while imagination embraces the entire world, and all there ever will be to know and understand.

                                                                      Comment


                                                                        Only pussies feel sick after booster shots.

                                                                        And so many getting Corona. It’s insane.

                                                                        Comment


                                                                          Tested positive.

                                                                          Went to get vitals taken and I was running a 102 fever. Took some Tylenol .. slept a bit .. fever has gone down.

                                                                          Throat feels shitty though.

                                                                          This literally feels like the flu I had
                                                                          Originally posted by curio
                                                                          Eat this protein bar, for it is of my body. And drink this creatine shake, for it is my blood.
                                                                          "If you can't handle me when I'm bulking, you don't deserve me when I'm cut." -- Marilyn Monbroe

                                                                          Comment


                                                                            Damn. Wtf is going on. So much for vaccination

                                                                            Comment


                                                                              Originally posted by KAC View Post
                                                                              Damn. Wtf is going on. So much for vaccination
                                                                              Not really, the vaccines sort of did their job in reducing mortality/illness (from Covid). They do almost nothing for transmission especially as time goes by (look at Gibraltar, Ireland and Israel) so they had to tweak their messaging on that one.

                                                                              However, the booster does almost nothing vs Omicron. People are being lied to when it comes to the booster in regards to Omicron. Thankfully Omicron appears to be an even more effective vaccine as it seems like it's low risk and highly contagious. *There's still delta around though so if you are concerned about Covid don't get too cocky yet.
                                                                              Originally posted by General Lee
                                                                              I've been praying for your nuts.
                                                                              Originally posted by General Lee
                                                                              If you must listen to country [music], play it backwards. You get your woman back, the dog comes back to life, Momma pops out from under the train, and it stops raining. :)

                                                                              Comment


                                                                                Originally posted by Nunz View Post
                                                                                Tested positive.

                                                                                Went to get vitals taken and I was running a 102 fever. Took some Tylenol .. slept a bit .. fever has gone down.

                                                                                Throat feels shitty though.

                                                                                This literally feels like the flu I had
                                                                                Hope you feel better soon.

                                                                                Comment


                                                                                  Originally posted by Nunz View Post
                                                                                  Tested positive.

                                                                                  Went to get vitals taken and I was running a 102 fever. Took some Tylenol .. slept a bit .. fever has gone down.

                                                                                  Throat feels shitty though.

                                                                                  This literally feels like the flu I had
                                                                                  Hope it passes quickly for you man.

                                                                                  Comment

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