The secret to losing weight: Balanced Gut bacteria

DorXtar · Nov 13, 2009, 01:11 AM

http://www.npr.org/templates/story/s...ryId=120318757

Then the team explored what would happen to these microbes if mice were switched from their standard low-fat, plant-rich mouse chow to a diet that was high in fat and sugar.

They found that in less than 24 hours the gut's microbial populations changed abruptly, according to a study in the journal Science Translational Medicine.

"We were quite amazed that the community really restructured itself in terms of the proportional representation of different bacterial species, the proportional representation of genes with different functions, in a very short period of time," says Gordon. "Certain members of that society of microbes became very dominant, and certain members became more diminutive."

And when this new collection of human microbes was transplanted into germ-free mice, the mice gained an increased amount of fat tissue even when fed low-fat diets, compared to mice that got human microbes from mice fed low-fat diets.

That was the biggest surprise for John Mekalanos, chairman of the department of microbiology and molecular genetics at Harvard Medical School, who co-wrote a commentary that appeared with the research report. "What it really suggests is that our biota really shape the way we respond to food," Mekalanos says.

Once again, I'd like to brag that I was ahead of science cuz I've been drinking kefir almost intuitively.

Zero · Nov 13, 2009, 01:23 AM

Sigh...

Quote:

No one currently knows if gut bugs are an important contributor to human obesity or if targeting them could lead to novel therapies. But Mekalanos says that this new study makes it more likely that scientists will be able to explore those possibilities "because one needs a pre-clinical model before one devises complicated, expensive human subjects trials."

DorXtar · Nov 13, 2009, 01:33 AM

Bah. Live a little zero. Put yourself out there. Don't wait for scientists to confirm things. Think for yourself for once.

forciano · Nov 13, 2009, 02:08 AM

Quote:

Originally Posted by DorXtar

http://www.npr.org/templates/story/s...ryId=120318757

Then the team explored what would happen to these microbes if mice were switched from their standard low-fat, plant-rich mouse chow to a diet that was high in fat and sugar.

They found that in less than 24 hours the gut's microbial populations changed abruptly, according to a study in the journal Science Translational Medicine.

"We were quite amazed that the community really restructured itself in terms of the proportional representation of different bacterial species, the proportional representation of genes with different functions, in a very short period of time," says Gordon. "Certain members of that society of microbes became very dominant, and certain members became more diminutive."

And when this new collection of human microbes was transplanted into germ-free mice, the mice gained an increased amount of fat tissue even when fed low-fat diets, compared to mice that got human microbes from mice fed low-fat diets.

That was the biggest surprise for John Mekalanos, chairman of the department of microbiology and molecular genetics at Harvard Medical School, who co-wrote a commentary that appeared with the research report. "What it really suggests is that our biota really shape the way we respond to food," Mekalanos says.

Once again, I'd like to brag that I was ahead of science cuz I've been drinking kefir almost intuitively.

Mmm I love kefir and yogurt...

DaJMasta · Nov 13, 2009, 02:43 AM

Another secret to loosing weight:

Exercise, don't eat food that's terrible for you, don't eat so much.

How much of each is different for everyone, but it's pretty universal.

Clockwork · Nov 13, 2009, 07:48 AM

The secret Dorxtar is the swine flu, pneumonia, and a lengthy hospital stay with some of that time with a feeding tube.

I lost 24lbs in 2 weeks.

(I joke, that is in no way a way to lose weight and it sucks trying to rehabilitate due to muscle loss and such)

Although I have changed my diet as well and have noticed since being in the hospital my bowel movements have been different (smooth, barely any need to wipe/tp looks clean). So perhaps that study is spot on and my intestines changed a bit. (I know, TMI)

Zero · Nov 13, 2009, 09:06 AM

Quote:

Originally Posted by DorXtar

Bah. Live a little zero. Put yourself out there. Don't wait for scientists to confirm things. Think for yourself for once.

ok dorxy-poo, you keep jumping to conclusions as a free-thinking man.

Djinn · Nov 13, 2009, 09:11 AM

"Bacteria?" Hrm. Perhaps, but my money is still on "eat healthy foods and get plenty of exercise."

ice · Nov 13, 2009, 09:32 AM

Quote:

Originally Posted by Djinn

"Bacteria?" Hrm. Perhaps, but my money is still on "eat healthy foods and get plenty of exercise."

Yep. People need to quit waiting around for "scientists" to "discover" things and just do the proven work.

AllexxisF1 · Nov 13, 2009, 10:03 AM

Thom Hartman was hitting on this subject a couple of months ago and I was enthralled with it.

Gut microbes and even worms have been effectively killed off in our systems for the past 20 years and maybe they shouldn't have.

I am paraphrasing the best I can recall but what he was getting on about with his guest that the removal of these worms and bacteria is what has led to obesity but even more so food allergies.

He discussed in length about how there are active research programs under way where subject are given the eggs to these worms. After a week or so when these worms begin to show up the subject have noticed all their food allergies and other allergic reactions have gone away.

Maybe the process of getting too sanitized in our lives was the wrong move.

Great article.

OzzieBloke · Nov 13, 2009, 10:35 AM

Eat less, move more.
Get your ass out the door.

caveman-jim · Nov 13, 2009, 11:50 AM

Quote:

Originally Posted by OzzieBloke

Eat less, move more.
Get your ass out the door.

Good hook for a song there, Ozzie!

DorXtar · Nov 13, 2009, 12:04 PM

Quote:

Originally Posted by Zero

ok dorxy-poo, you keep jumping to conclusions as a free-thinking man.

FrAg Of FuRy · Nov 13, 2009, 12:11 PM

I have a rigorous masturbation regimen I follow daily and it keeps the pounds off.

That and all the digging and filling of holes in my back yard.

**MyTMouse** · Nov 13, 2009, 12:12 PM

Move Less, Eat more
'till you can't get out the door
Get sick? Just make a call
and firemen will take down your wall
Flat broke? Don't worry bro
You'll soon appear on some talk show
Take advantage of your look
you can write a best-selling book
Money's in, the women drool
The skinny bitches are the fools

word

phial · Nov 13, 2009, 12:43 PM

just become a semi-vegetarian for a while.. like stick to fish, eat nothing but grains and veggies/fruits otherwise. youll look like an Ethiopian in a few months.

ice · Nov 13, 2009, 12:46 PM

I have decided I really hate this "study".

Auric · Nov 13, 2009, 01:01 PM

Tape worms for victory.

OzzieBloke · Nov 13, 2009, 10:00 PM

Quote:

Originally Posted by MyTMouse

Move Less, Eat more
'till you can't get out the door
Get sick? Just make a call
and firemen will take down your wall
Flat broke? Don't worry bro
You'll soon appear on some talk show
Take advantage of your look
you can write a best-selling book
Money's in, the women drool
The skinny bitches are the fools

word

If that is an original work of yours, MyT, I'm going to lay down a fat beat and put that over the top of it and cred you for it. Make a vid. Youtube. Fat-ass fame...

VVanks · Nov 13, 2009, 10:26 PM

Dorxtar is a perfect example of confirmation bias.

DorXtar · Nov 13, 2009, 10:36 PM

Stop following me around stalker!

Dr. Zhivago · Nov 13, 2009, 11:00 PM

Quote:

Originally Posted by FrAg Of FuRy

I have a rigorous masturbation regimen I follow daily and it keeps the pounds off.

That and all the digging and filling of holes in my back yard.

Reason #1: 4 Reasons to Carry a Shovel At All times

DaJMasta · Nov 13, 2009, 11:28 PM

Quote:

Originally Posted by Auric

Tape worms for victory.

It is certainly tough for science to beat the effectiveness of parasites. Though we're ok at beating the parasites now.

DorXtar · Nov 13, 2009, 11:30 PM

Where is cavemanjeff when you need him.

Nov 13, 2009, 01:11 AM	#1	Advertisement (Guests Only) Login or Register to remove this ad
DorXtar mildly retarded Join Date: Dec 2002 Location: REPUBLI FRIENDS!!! Posts: 18,473	The secret to losing weight: Balanced Gut bacteria http://www.npr.org/templates/story/s...ryId=120318757 Then the team explored what would happen to these microbes if mice were switched from their standard low-fat, plant-rich mouse chow to a diet that was high in fat and sugar. They found that in less than 24 hours the gut's microbial populations changed abruptly, according to a study in the journal Science Translational Medicine. "We were quite amazed that the community really restructured itself in terms of the proportional representation of different bacterial species, the proportional representation of genes with different functions, in a very short period of time," says Gordon. "Certain members of that society of microbes became very dominant, and certain members became more diminutive." And when this new collection of human microbes was transplanted into germ-free mice, the mice gained an increased amount of fat tissue even when fed low-fat diets, compared to mice that got human microbes from mice fed low-fat diets. That was the biggest surprise for John Mekalanos, chairman of the department of microbiology and molecular genetics at Harvard Medical School, who co-wrote a commentary that appeared with the research report. "What it really suggests is that our biota really shape the way we respond to food," Mekalanos says. Once again, I'd like to brag that I was ahead of science cuz I've been drinking kefir almost intuitively. __________________ Treat the cause, not the symptom. [Honda] - Low maintenance vehicles, [H]igh maintenance people.™ KNOCKING

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Nov 13, 2009, 01:33 AM	#3
DorXtar mildly retarded Join Date: Dec 2002 Location: REPUBLI FRIENDS!!! Posts: 18,473	Bah. Live a little zero. Put yourself out there. Don't wait for scientists to confirm things. Think for yourself for once. __________________ Treat the cause, not the symptom. [Honda] - Low maintenance vehicles, [H]igh maintenance people.™ KNOCKING

Nov 13, 2009, 02:43 AM	#5
DaJMasta Baffoonist Join Date: Sep 2005 Location: Austin, Texas Posts: 7,244	Another secret to loosing weight: Exercise, don't eat food that's terrible for you, don't eat so much. How much of each is different for everyone, but it's pretty universal. __________________ Desktop: Intel Core i7 860 : 8GB Corsair DDR3 1600 : Sapphire HD5750 1GB : Gigabyte P55M-UD4 : Asus Xonar DX : Intel X25-M 80GB and 500GB 7200.11 SATAII hard drives : Corsair 400W PSU : Samsung T240 24" Monitor : Windows 7 Pro x64 Laptop: Asus Eee PC 900HA : 1.6GHz Intel Atom N270 : 2GB DDR2 800 : GMA 950 Integrated : Intel 945GSE Chipset : 160GB Seagate Momentus 5400.4 hard drive : 36W Power brick and battery : ALC262 Integrated Sound : 8.9" LCD : Windows XP Home Lil' Red: Intel Pentium Dual Core e5200 : 4GB SLI Ready OCZ DDR2 800 : GeForce 9300m Integrated + various low end discrete cards: Zotac 9300-ITX Wifi Motherboard : 100GB Hitachi 7200rpm SATA laptop hard drive : 80W power brick and picoPSU150 XT : Integrated HD Audio : Windows 7 Pro For Sale/Trade Thread http://www.medpants.com/

Nov 13, 2009, 07:48 AM	#6
Clockwork Rage3D Veteran Join Date: Mar 2001 Location: Wisconsin Posts: 11,777	The secret Dorxtar is the swine flu, pneumonia, and a lengthy hospital stay with some of that time with a feeding tube. I lost 24lbs in 2 weeks. (I joke, that is in no way a way to lose weight and it sucks trying to rehabilitate due to muscle loss and such) Although I have changed my diet as well and have noticed since being in the hospital my bowel movements have been different (smooth, barely any need to wipe/tp looks clean). So perhaps that study is spot on and my intestines changed a bit. (I know, TMI) __________________ Last edited by Clockwork : Nov 13, 2009 at 07:50 AM.

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Nov 13, 2009, 09:11 AM	#8
Djinn Rage3D Fixture Join Date: Mar 2001 Location: Warminster, PA USA Posts: 23,910	"Bacteria?" Hrm. Perhaps, but my money is still on "eat healthy foods and get plenty of exercise." __________________ "Conscience is the inner voice that warns us somebody may be looking." - H. L. Mencken (1880 - 1956)

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Nov 13, 2009, 10:03 AM	#10
AllexxisF1 Butter's Fan Club. Join Date: Nov 2002 Location: Treasure Coast, Florida Posts: 3,942	Thom Hartman was hitting on this subject a couple of months ago and I was enthralled with it. Gut microbes and even worms have been effectively killed off in our systems for the past 20 years and maybe they shouldn't have. I am paraphrasing the best I can recall but what he was getting on about with his guest that the removal of these worms and bacteria is what has led to obesity but even more so food allergies. He discussed in length about how there are active research programs under way where subject are given the eggs to these worms. After a week or so when these worms begin to show up the subject have noticed all their food allergies and other allergic reactions have gone away. Maybe the process of getting too sanitized in our lives was the wrong move. Great article. __________________ Business! Mankind was my business. The common welfare was my business; charity, mercy, forbearance, and benevolence, were all my business. The dealings of my trade were but a drop of water in the comprehensive ocean of my business!

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Nov 13, 2009, 10:35 AM	#11
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Nov 13, 2009, 12:11 PM	#14
FrAg Of FuRy Rage3D's Village Idiot Join Date: Jun 2008 Location: Illinois Posts: 4,315	I have a rigorous masturbation regimen I follow daily and it keeps the pounds off. That and all the digging and filling of holes in my back yard. __________________

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Nov 13, 2009, 12:12 PM	#15
MyTMouse Console Forumas Modamus Join Date: Nov 2000 Location: GTA (Southern Ontario) Posts: 6,730	Move Less, Eat more 'till you can't get out the door Get sick? Just make a call and firemen will take down your wall Flat broke? Don't worry bro You'll soon appear on some talk show Take advantage of your look you can write a best-selling book Money's in, the women drool The skinny bitches are the fools word

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Nov 13, 2009, 12:43 PM	#16
phial The descent of electrons. Join Date: May 2003 Posts: 14,894	just become a semi-vegetarian for a while.. like stick to fish, eat nothing but grains and veggies/fruits otherwise. youll look like an Ethiopian in a few months. __________________ There are no things, only processes.

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Nov 13, 2009, 12:46 PM	#17
ice Rage3D Veteran Join Date: Jan 2003 Location: PA Posts: 15,365	I have decided I really hate this "study". __________________ X3350 (3.6GHZ)\|4GB of GSkill\|500GB + 320GB SATA\|MSI 8800GTS OC 512MB \|Abit IP35 Pro\|Windows Vista 64 Ultimate 360 games

Nov 13, 2009, 01:01 PM	#18
Auric Je t'aime Join Date: Feb 2002 Posts: 2,649	Tape worms for victory. __________________ Look on the bright side, one day our sun will supernova and this won't even be a memory.

Nov 13, 2009, 10:26 PM	#20
VVanks W A N K E Y ! Join Date: Jan 2004 Location: Toronto, Canada Posts: 3,968	Dorxtar is a perfect example of confirmation bias. __________________ -------------------------- \ \|\ \| /¯\ \|\\| \|/ \|¯ .\\| \\| \|¯\| \| \| \|¯\ ¯\| -------------------------- http://wankey.deviantart.com

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Nov 13, 2009, 10:36 PM	#21
DorXtar mildly retarded Join Date: Dec 2002 Location: REPUBLI FRIENDS!!! Posts: 18,473	Stop following me around stalker! __________________ Treat the cause, not the symptom. [Honda] - Low maintenance vehicles, [H]igh maintenance people.™ KNOCKING

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Nov 13, 2009, 11:30 PM	#24
DorXtar mildly retarded Join Date: Dec 2002 Location: REPUBLI FRIENDS!!! Posts: 18,473	Where is cavemanjeff when you need him. __________________ Treat the cause, not the symptom. [Honda] - Low maintenance vehicles, [H]igh maintenance people.™ KNOCKING

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